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Finally, we identified several microbes that correlated with immune readouts in both fecal recipients and donors, and with in vitro HIV infection, which suggests a role for gut microbiota in immune activation and potentially HIV acquisition in MSM.The communities of commensal microbes that colonize the human gut comprise the gut microbiome, which has been shown to play a significant role in shaping the immune system. Recent studies have reported a distinct gut microbiome composition in men who have sex with men (MSM) exhibiting HIV risk behaviors when compared with low risk men who have sex with women (MSW), regardless of their HIV infection status. Whether these gut microbiome differences in high risk MSM directly impact immune activation is important to understand since increased T cell activation is associated with increased HIV transmission risk and more severe disease.

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No asking for valuation. No asking how or where to do these either.More information about Rule 8For information regarding this and similar issues please see the sidebar to the right or the subreddit rules, for a more detailed analysis of our rules. If you have questions you can contact the moderator team through modmail.

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